Correlation between triglycerides and glutamic-pyruvic transaminase in men on high-fat diets.

Of eight young men on high.fat diets (60% of caloric intake) for 42 days, four developed serum glutamic-pyruvic tra nsaminase concentrations greater than normal, while lactic dehydrogenase, glutamic-oxalacetic transaminase, and alkaline and acid phosphatases were within the normal range. Serum triglyceride levels were also within the normal range, but significant correlations between serum triglycerides and glutamic-pyruvic transaminase levels were found in six of the eight subjects; the mean values for all eight subjects showed a correlation significant at the 99% level of confidence. SGPT levels may be of fundamental significance along with blood triglycerides in the evaluation of fatty livers and coronary artery disease.